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Schizophrenia, Bipolar, or Major Depressive Disorder and Postacute Sequelae of COVID-19

People with serious mental illness (SMI) diagnoses (e.g., schizophrenia, bipolar disorder, or recurrent major depressive disorder) have an increased risk of COVID-19 infection and related mortality. This risk can be attributed to limited access to medical care, challenges in treatment adherence, and the presence of comorbidities. However, it remains uncertain whether the same risks extend […]

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NIH Grant Will Fund Autism Research Replication, Validation, and Reproducibility Center

Investigators at Weill Cornell Medicine and Cornell’s Ithaca campus have received a $5.1 million, three-year grant from the National Institutes of Health’s Autism Data Science Initiative (ADSI) to launch the Autism Replication, Validation, and Reproducibility (AR²) Center. The center aims to improve the reliability of autism research and foster public trust in the field. “The

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Association of Past-Year Mental and Physical Health Conditions With Intentional or Unintentional Drug Overdoses

In 2023, the US reported approximately 108,000 deaths from overdose. Intentional overdoses, sometimes referred to as self-inflicted or suicide-related overdoses, occur when an individual deliberately consumes a harmful amount of drugs with the intent to self-harm or end one’s life. Overdoses classified as unintentional often result from accidental consumption of drugs in excessive quantities. While intentional overdose deaths have decreased since the mid-2010s, unintentional overdose deaths have increased

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Weill Cornell Medicine-Led Consortium Receives $13.5 Million to Expand Patient Data Network

The INSIGHT Clinical Research Network (CRN), a database of more than 23 million patient health records, has received $13.5 million in renewed funding from the Patient-Centered Outcomes Research Institute (PCORI). The renewed funding will support efforts to lead and conduct research of national scope over the next four years, increasing capacity for observational studies, retrospective studies, clinical trials, machine

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Identification of risk factors of Long COVID and predictive modeling in the RECOVER EHR cohorts

Growing evidence indicates the existence of post-acute and long-term effects of COVID-19, called post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. However, few studies have developed machine learning tools to identify risk factors that might make someone more likely to develop long COVID. This may be attributed to the heterogeneity of PASC conditions or small sample sizes of patient data.  To address these challenges, a data-driven study in Communications Medicine led by  Dr. Rainu Kaushal, senior associate dean for clinical

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Machine Learning Helps Define New Subtypes of Parkinson’s Disease

Researchers at Weill Cornell Medicine have used machine learning to define three subtypes of Parkinson’s disease based on the pace at which the disease progresses. In addition to having the potential to become an important diagnostic and prognostic tool, these subtypes are marked by distinct driver genes. If validated, these markers could also suggest ways

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Association of opioid or other substance use disorders with health care use among patients with suicidal symptoms

Substance use disorders (SUDs), including opioid use disorder (OUD), and drug overdose deaths in the United States reached an all-time high with the Centers for Disease Control and Prevention between April 2020 and April 2021, reporting more than 100,000 overdose deaths. Previous studies indicate that patients with chronic pain or mood disorders are more likely to receive opioid medications than patients without these conditions and are at

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Increases in Pediatric Mental Health Emergency Visits Persist Throughout Pandemic

Mental health crises among children and adolescents requiring emergency department care skyrocketed during the pandemic and have stayed elevated despite a return to normalcy, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators. The study, published in the journal Pediatrics on Oct. 20, compared rates of pediatric mental health visits in the emergency

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Study Discovers Long COVID Risk and Symptoms Vary in Different Populations

While the peak of the COVID-19 pandemic seems to have passed, the effects of post-COVID conditions on public health remain. A new study led by Weill Cornell Medicine and NewYork-Presbyterian investigators has found that the risk of long COVID and its symptoms present very differently across diverse populations and suggests that further investigation is needed

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