Featured Studies

RECOVER (Researching COVID to Enhance Recovery)

RECOVER is a national initiative, funded by the National Institutes of Health, designed to advance scientific knowledge of Post-acute Sequelae of SARS-CoV-2 (PASC) through patient-centered research. RECOVER aims to 1) understand the clinical spectrum of and biology underlying recovery of acute PASC 2) define risk factors associated with PASC and distinct phenotypes of patients who have prolonged symptoms, 3) examine PASC overtime and its relationship with other diseases and 4) identify potential treatments for patients with PASC. Leveraging the Patient-Centered PCORnet to form the RECOVER Adult and Pediatric PCORnet EHR Hubs, the Adult Center at Weill Cornell Medicine (WCM) and Pediatric Center based at the Children’s Hospital of Philadelphia (CHOP) have been awarded to develop a single, unified EHR/ORWD repository to study Long COVID across 41 adult and pediatric institutions nationwide.

Led Drs. Rainu Kaushal and Jessica Ancker, this PCORnet^® Study links clinical data from three CRNs (INSIGHT, STAR, OneFlorida+) to Medicare Claims. As secondary analysis, the study replicates the Medicare analysis using commercial claims data from Medical Outcomes Management and Humana Healthcare Research for commercially insured populations. Leveraging these data linkages, the research team applies natural experiment methods to compare the effectiveness of (1) synchronous telemedicine alone; (2) telemedicine-supplemented in-person care; and (3) in-person care alone on patient-centered outcomes, including the quality of health care and the frequency of avoidable emergency department visits. INSIGHT serves as the Coordinating Center for this study.

Comparative Effectiveness of Telemedicine

PREVENTABLE (Pragmatic Evaluation of Events and Benefits of Lipid-Lowering in Older Adults)

PREVENTABLE seeks to explore how taking a statin could prevent dementia, disability, or heart disease in older adults and help live longer, healthier lives. PREVENTABLE is a PCORnet^® Study and is funded by the National Institute of Aging and the National Heart, Lung, & Blood Institute of the National Institutes of Health.